Comment from barbara.wilkey

Excellent

These three are well on their way to solving this problem. Dana is doing her thing, but I can't help but believe this is the calm before the storm and it's going to be a gigantic storm. I am enjoying this story.

 Comment Written 03-Jan-2025

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reply by the author on 03-Jan-2025

Batten down the hatches. There's a red sky in the morning. That won't be for a while, though.

Comment from Michael Ludwinder

Excellent

I really enjoyed how your story includes technical intrigue. The dialogue felt so natural. Especially Patty's distinct voice. I could practically hear her on the phone. The concept of using science to tackle such a unique problem is fascinating. I also liked how you gave just enough detail about the plan to keep me curious without making it feel overwhelming. Great job setting the stage for something exciting - I can't wait to see what happens next!

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 Comment Written 03-Jan-2025

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reply by the author on 03-Jan-2025

Thank you so much, Michael. I was a little worried about this chapter (as you could tell from the disclaimer), but I'm glad to hear you found it understandable and with the right amount of detail.

Comment from Wayne Fowler

Excellent

Simple enough plan. I'm just having trouble trying to figure how the operation needs a mathematician. But I can hold on.
Nice that Brian and Julia could build (and furnish) a mansion-size home.
Nicely written. Good work.

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 Comment Written 03-Jan-2025

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reply by the author on 03-Jan-2025

Thanks very much, Wayne. You won't see much of an attempt on my part to explain the mathematics involved, mainly because I have almost no understanding of it myself nor know how to explain it in such a way that readers will take much from it.

Here are some examples of the role of higher mathematics from my research:

"Higher-level statistics are used to determine associations between genetic variants and traits, requiring knowledge of probability and statistical inference."

"Algorithms for aligning DNA, RNA, or protein sequences can involve complex mathematical concepts, including dynamic programming and graph theory."

"Mathematical modeling is used to simulate biological processes, requiring differential equations and linear algebra to understand complex interactions in gene regulation and metabolic pathways."

In my next chapter there will be a vague reference to this, but beyond that, I just didn't want to overwhelm readers any more than I already have.

reply by Wayne Fowler on 03-Jan-2025

overwhelmed we would be